Holo is the wolf spirit from Spice and Wolf, the light novel series by Isuna Hasekura with illustrations by Ju Ayakura, and of the 2008 anime adaptation where Ami Koshimizu voices her. She appears as a girl of about fifteen with wolf ears and a white-tipped tail, though her true form is a huge wolf. She calls herself the Wise Wolf of Yoitsu, a harvest spirit who was worshipped for centuries in the village of Pasloe.

She travels as the companion of the merchant Kraft Lawrence